Kubva kushandiswa kukuvadza - imwe danho
Kusvikira muzana remakore rechi20, zvirwere zvinotapukira ndizvo zvakakonzera rufu. Mazuva ano zvakaoma kufungidzira kuti chirwere chinowanzogona kuuraya mamiriyoni evanhu. Kunyange zvakadaro, iyi ndiyo mamiriro acho ezvinhu: "Mukurumbira" weChirungu wa1918-1919 unozivikanwa wakaurawa, maererano nekufungidzira kwakasiyana, vanhu vane mamiriyoni 50 kusvika ku100, kana kuti 2.7-5.3% yevanhu venyika. Zvadaro, vanenge mamiriyoni 550 vakatapukirwa - 29.5% yevanhu venyika. Kutanga mumwedzi yekupedzisira yeHondo Yenyika Yenyika Yese, muSpanish wakakurumidza kupfuura nhamba yevakashungurudzwa ropa iri guru pane iyo nguva. Hazvishamisi kuti munhau yose, vanhu vave vachitsvaka nzira dzokurwisa zvirwere zvinotapukira. Kuchinja kukuru mumamiriro acho ezvinhu kwakatanga muzana ramakumi maviri remakore, apo bhakitiriya weChirungu Alexander Fleming akawana antibiotic penicillin muna 1928. Kare muna 1944, apo mapoka ekutsvakurudza eAmerica nevagadziri vakakwanisa kugadzira purogiramu yekushanda kwepenicillin, kufa kwebhakitiriya maonda maonda mumunda weHondo Yenyika II yakaramba zvakanyanya.Zvakanaka here?
Pasina mubvunzo, nekugadzirwa kwemishonga inorwisa mabhakitiriya, mushonga wepasi rose wakaita nhanho huru mberi. Zvirwere zvakawanda, zvisati zvaonekwa sokuti hazvigoneki, zvakapinda munguva yakapfuura. Zvinotarisirwa kutaura kuti pamagumo ezana remakore rechi19, zvirwere zvinotapukira zvinokwana 45% yehuwandu hwekufa kwehuwandu hwevanhu. Muna 1980, chiyero ichi chakaderedzwa kusvika 2% chete. Kutungamira kwakakosha mukuchinja kwakakosha kwakaitwa nekuwanikwa kwemishonga inorwisa mabhakitiriya.Zvisinei, sechiremba chero upi zvake anoziva, mishonga yakachengeteka yakakwana haina kubudirira. Izvi zvinoshanda kumishonga inorwisa mabhakitiriya yakazara. Muchikamu chechipiri chezana remakore rechimakumi maviri, vanachiremba munyika yose vanorayira madhiragi eboka iri kumamiriyoni evarwere, kusanganisira vana, sezvikonzero zvekuti nhasi vanhu vanotambura nekuwedzerwa, chirwere cheshuga, chirwere chetachiona, chirwere cheputi uye zvimwe zvirwere zvakakomba. Izvozvo zvakaitika kuti maantibayoti, paanoparadza zvirwere zvinokuvara zvinokuvadza, zvose panguva imwechete zvinokanganisa zvakanyanya mukati me microflora mukati memuviri womunhu, pakutanga - kumakoromine ematumbo anodiwa pakudyiwa kwakakodzera.
Chii chinoparadza dysbiosis?
Kubviswa kwemuvara wepachiviri microflora nemapathogen semugumisiro wekutora antibiotics, kana kuti dysbiosis, kazhinji hazviitike mune rimwe zuva - uye ichi ndicho ngozi huru. Vashomanana vanogona kusonganisa nguva nenguva nekudzoka kwezvirwere zvekudya, zvigaro zvinetso nekutora antibacterial drugs.Panguva imwecheteyo, kuongororwa kwemishonga inorwisa mabhakitiriya inoratidzirwa gore negore mu 5-30% yevarwere vakagamuchira mushonga unorwisa mabhakitiriya! Vakawanda vavo vanonyunyuta nezvekugumburwa kwechigarire kana kugadziriswa kwechigaro, icho chinoitika nekuda kwekuputsa kwe metabolism ye bile acids uye makhahydrates muhumu. Ichi ndechokuti chiyero chemakiromita anodiwa pakugadzirisa kwakakwana kwakaderedzwa zvakanyanya mumuviri. Kushandurwa kwehutano hwepachivi microflora, uyewo, kunotungamirira kusakanganisika mubasa rezvimwe zvirongwa zvakakosha zvemuviri womunhu, kunyanya maitiro ezvirwere zvemuviri.
Muchiitiko ichi, munhu anotora maantibioti, asina chero chinokonzera, ane zvirwere zvakasiyana-siyana: atopic dermatitis, eczema, cystitis inowanzoitika, nguva dzose SARS, autoimmune colitis, kuneta, hyperlipidemia, nezvimwewo. Nhamo, kuedza kubvisa zviratidzo zvezvirwere izvi pasina kuchinja - intestinal dysbiosis - haunounzi nguva yakareba yakagadzikana chigumisiro. Asi muna 1993 mutapi wenyanzvi wokuFrance J. Pulvertye akaita sangano rakaratidza kuti: kushandiswa kwemishonga inorwisa mabhakitiriya mumakore maviri ekutanga ehupenyu hwomunhu, pasinei nemigumisiro yezvimwe zviitiko, kunowedzera kukanganisa kwechirwere, atopic dermatitis uye eczema ka4-6!
Zvinongokuvadza here?
Chii chingaita mumamiriro ezvinhu apo kurapwa kwemishonga inouraya inokosha muupenyu? Mhinduro yacho inoratidzika pachena: zvakakosha kuderedza kuipa kwemishonga inorwisa mabhakitiriya mukati me microflora yemuviri. Panenge kubva pakati pezana remakore rechimakumi maviri, masayendisiti munyika dzakasiyana akatanga kushandiswa zvinhu zvinogona "kuvonga" muviri wedu patinotora antibiotics. Muna 1954, kwekutanga, izwi rokuti "probiotic" (rechiGiriki rokuti "pro" - nokuda, uye "bios" - "upenyu") zvakatanga kuonekwa, izvo zvakazozivikanwa sekugadzirira kunodzivirira microflora kubva pakuparadzwa.Mazuva ano, kune maitiro akawanda akasiyana-siyana emishonga inodhaka, izvo zvinogona kuderedza kukuvara kunokonzerwa nemuviri kuburikidza nokutora maantibiotics. Saka, iyo inonzi polycomponent inonzi rioflora balance inobvumira kuchengetedza chirwere chekudya nemhaka yehuwandu hwehuwandu hwemakirini emagetsi: bifido- uye lactobacillus, uye streptococci. Izvi zvisikwa zvipenyu zvinokonzerwa nekudzivirira muviri nekuda kwekusimudzira kwekuumbwa kwepachiviri microflora. Zvisinei, urongwa uhwu hunoshanda chete pamishonga yemishonga ine tsananguro yakanyatsorondedzerwa yezvipingamupinyi / mhando dzebhakitiriya, nhamba yebhakitiriya inopupurirwa ne "kupona" kwebhakitiriya mune chirwere chemuviri, kushanda, kuchengeteka uye zvakachengetedza mararamiro ehupenyu. Nesarudzo yakakodzera yekurapa maitiro uye kuchengetwa kwezvirongwa zvekuenda kunechiremba, mushonga unorwisa mabhakitiriya unozobvisa chirwere chinotapukira pasina kusiya "zvishumbiso" zvisingafadzi zvose zviri mberi uye munguva iri mberi.