Basa rekudzivirirwa kwemasikirwo emumunhu mukuberekwa kwevanhu rakakwirira chaizvo. Masayendisiti akaratidza kuti pamusoro pechishanu chevanhu vane kusadudzwa kusina kutsanangurwa vane matambudziko nemusununguko wemuviri. Chimwe chezvinhu zvinosanganiswa nemasimba ezvirwere, izvo zvinogona kutungamirira pakushaya simba, ndiko kushandiswa kwemitumbi yeAntispermal.
Iyi miviri inobatanidzwa mukugadzirisa kwema gametes (gametes), kusabvumira spermatozoa kupinda mazai evha. Iyo nzira yavanoita izvi haisati yave yakanzwisiswa zvakakwana, asi yakatojekesa kuti ma antibodies anovhara acrosomal response ye spermatozoon masero, anoshanda seimwe yezvinhu zvinodiwa kuti zvibudirire fertilization. Kana mumwe wevamwe varume, varume kana vakadzi, ane miviri yeAntispermic, ipapo hutano hwembryo hunowanzoipisisa kupfuura yevanhu vasina miviri yakadai, iyo inoderedza kubudirira kwekusagadziriswa kwehutano ne in vitro fertilization. Kana iyo ACAT isingabatsirwi kutarisirwa nemaitiro ekuchengetedza, nzira inonyanya kufarirwa yevakadzi vaviri vakadaro ndiyo kuiswa kwepermatozoa muzai (ICSI).
Nzira dzokugadzirisa antisperm antibodies mumadzimai
Mumiririri wehutachiona husina simba, antisperm antibodies anogadziriswa mumushonga wemukati uye mu plasma yeropa. Izvo zvinotenderwa kuedza kuvepo kwezvirwere zvakadaro mukati mavo vakaroorana vari kugadzirira IVF.
Kazhinji kazhinji mukugadzirisa kweAntisperm antibodies, nzira dzinobva pakugadziriswa kwezvirwere zvinorwisana nemakumbo antigens zvinoshandiswa. Izvi zvinosanganisira nzira dzakadai se:
- Chiyero chekubatana kwepermatozoa nemuchengeterwe wemukati, kana postcoital. Inofanira kurangarirwa kuti chimwe chezvikonzero zvinowanzokonzera mushure mokuongorora mushure memazuva ano ndezvokuti pane ACAT mumurume, kureva, dambudziko rakabatana nemurume, kwete kumuromo wechibereko. Zvisinei, inowanzokwanisika kuchengeta kusanganiswa kwevakadzi nevakadzi kunokonzera. Postcoital test haisi yakatendeseka zvikuru pakuongorora kusununguka uye kwaari peresenti yenhoroondo dzenhema yakanyanya kwazvo. Ichi ndicho chikonzero hachisati chichishandiswa chete, chete pamwe chete nemashoko kubva kutsvakurudzo pa ACAT;
- MAR-muedzo. Iyi ndiyo nzira inokubvumira kuti uone nhamba ye spermatozoa inobatanidzwa nemasikirwo emakirasi IgA neGGG, uye inobatsira kuziva mazita eAntisperm antibodies mune zvakadai semasikironi semukomana wemukati, spermoplasm, plasma yeropa. Uyu muedzo unozivikanwa pasi rose sehutano hwekuongororwa hwe ACAT, hunova nekunzwisisa kwepamusoro uye hukuru hwehutano;
- Iyo latex agglutination test inobva ichangobva kusimbiswa uye isina kuongororwa zvakazara ACAT muedzo. Uyu muedzo inzira yakananga yekuziva ACAT muzvinhu zvinokonzerwa nehupenyu, zvakadai se plasma yeropa, mbeu, chiberekero chechibereki. Ane senzwiro yakakwirira. Nheyo yezvirwere zvinogona kuonekwa achishandisa nzira iyi haisi nguva dzose yakafanana neyero yezvirwere zvinotarirwa nezviyero zviviri zvekare, saka dzinowanzobatana kuti dziwane zvizere zvakawedzerwa;
- ELISA (enzyme immunoassay) - inowanzoshandiswa kutsvaga ACAT mu plasma yeropa. Inotaridzirwa imwe yevamwe nzira dzekuongorora ACAT. Mabhii makuru eAACAT, ayo anotsanangurwa nenzira iyi muropa rema plasma kuvakadzi, haafaniri kusanganiswa nekuderera mukutanga kwekuzvimba.
Nzira dzokurapa
Kurapa kwevakaroorana avo vakaonekwa kuti vane huwandu huwandu hweAACAT inogona kuitika nenzira dzakasiyana, zvichienderana nemigumisiro yekuongorora. Chokutanga, pane dzimwe nguva, nzira yekudzivirira inoshandiswa, kureva, kondomu, uye inoshandiswa nguva dzose kwemwedzi miviri kusvika ku5 kana kuti mukati memo, iyo kondomu isingashandisi chete mumazuva iwayo anofanirwa pakuonekwa kwehutumbi.
Kuderedza kuwanda kwemuviri uri kupinda mumuviri wemukadzi kunokonzera kuderera kwekushandiswa kwemasimba uye kunowedzera mikana yekudzivirira.
Panguva imwecheteyo, kurapa kunogona kurongerwa, izvo zvinoderedza visikiti yechipical mucus uye inhibits the synthesis of ACAT muvakaroorana. Kana nzira dzakachengetedza dzisingabatsiri, zvino dzinoenda kuIkI.